HPVomics

A therapeutic and epitome resource for Human Papillomaviruses

Efficient putative HR-HPVs E8^E2 protein epitopes (MHC-II Binders)

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S.No.	HPV type	Target region	Peptide seuences	Start	End	Allele	Method	Percentile rank
1	HPV31	E8^E2	LKCLRYRLSKYKQLY	117	131	HLA-DRB5*01:01	Consensus	0.13
2	HPV31	E8^E2	ILKCLRYRLSKYKQL	116	130	HLA-DRB5*01:01	Consensus	0.18
3	HPV56	E8^E2	KCCRYRFQKYKTLFV	117	131	HLA-DRB1*07:01	Consensus	0.18
4	HPV31	E8^E2	KCLRYRLSKYKQLYE	118	132	HLA-DRB5*01:01	Consensus	0.2
5	HPV31	E8^E2	ANILKCLRYRLSKYK	114	128	HLA-DRB1*11:01	Consensus	0.24
6	HPV56	E8^E2	CCRYRFQKYKTLFVD	118	132	HLA-DRB1*07:01	Consensus	0.31
7	HPV51	E8^E2	CFRYRFTKHKGLYKN	110	124	HLA-DRB1*11:01	Consensus	0.32
8	HPV53	E8^E2	LRYRFQKHKQLFVTV	129	143	HLA-DRB1*07:01	Consensus	0.33
9	HPV31	E8^E2	NILKCLRYRLSKYKQ	115	129	HLA-DRB1*11:01	Consensus	0.34
10	HPV59	E8^E2	LKCLRYRLRKVHWLF	109	123	HLA-DRB1*11:01	Consensus	0.34
11	HPV53	E8^E2	CLRYRFQKHKQLFVT	128	142	HLA-DRB1*07:01	Consensus	0.35
12	HPV53	E8^E2	RYRFQKHKQLFVTVS	130	144	HLA-DRB1*07:01	Consensus	0.35
13	HPV31	E8^E2	DANILKCLRYRLSKY	113	127	HLA-DRB1*11:01	Consensus	0.36
14	HPV53	E8^E2	KCLRYRFQKHKQLFV	127	141	HLA-DRB1*07:01	Consensus	0.36
15	HPV31	E8^E2	NILKCLRYRLSKYKQ	115	129	HLA-DRB5*01:01	Consensus	0.37
16	HPV35	E8^E2	LKCLRYRLGKYKALY	111	125	HLA-DRB5*01:01	Consensus	0.37
17	HPV82	E8^E2	LKCLRYRFAKHRNLF	109	123	HLA-DRB5*01:01	Consensus	0.37
18	HPV82	E8^E2	KCLRYRFAKHRNLFK	110	124	HLA-DRB5*01:01	Consensus	0.37
19	HPV82	E8^E2	CLKCLRYRFAKHRNL	108	122	HLA-DRB5*01:01	Consensus	0.38
20	HPV82	E8^E2	CLRYRFAKHRNLFKE	111	125	HLA-DRB5*01:01	Consensus	0.38
21	HPV82	E8^E2	LRYRFAKHRNLFKEV	112	126	HLA-DRB5*01:01	Consensus	0.38
22	HPV82	E8^E2	RYRFAKHRNLFKEVS	113	127	HLA-DRB5*01:01	Consensus	0.38
23	HPV82	E8^E2	YRFAKHRNLFKEVSS	114	128	HLA-DRB5*01:01	Consensus	0.38
24	HPV82	E8^E2	PNTGGHLSATKTAFI	85	99	HLA-DRB1*07:01	Consensus	0.38
25	HPV31	E8^E2	CLRYRLSKYKQLYEQ	119	133	HLA-DRB5*01:01	Consensus	0.39
26	HPV51	E8^E2	FRYRFTKHKGLYKNV	111	125	HLA-DRB1*11:01	Consensus	0.4
27	HPV56	E8^E2	CRYRFQKYKTLFVDV	119	133	HLA-DRB1*07:01	Consensus	0.4
28	HPV31	E8^E2	ILKCLRYRLSKYKQL	116	130	HLA-DRB1*11:01	Consensus	0.42
29	HPV51	E8^E2	LKCFRYRFTKHKGLY	108	122	HLA-DRB5*01:01	Consensus	0.42
30	HPV51	E8^E2	KCFRYRFTKHKGLYK	109	123	HLA-DRB5*01:01	Consensus	0.42
31	HPV51	E8^E2	CLKCFRYRFTKHKGL	107	121	HLA-DRB5*01:01	Consensus	0.43
32	HPV51	E8^E2	CFRYRFTKHKGLYKN	110	124	HLA-DRB5*01:01	Consensus	0.43
33	HPV51	E8^E2	FRYRFTKHKGLYKNV	111	125	HLA-DRB5*01:01	Consensus	0.43
34	HPV51	E8^E2	RYRFTKHKGLYKNVS	112	126	HLA-DRB5*01:01	Consensus	0.43
35	HPV51	E8^E2	YRFTKHKGLYKNVSS	113	127	HLA-DRB5*01:01	Consensus	0.43
36	HPV26	E8^E2	TNSLKCLRYRFKKHK	118	132	HLA-DRB5*01:01	Consensus	0.48
37	HPV31	E8^E2	ANILKCLRYRLSKYK	114	128	HLA-DRB5*01:01	Consensus	0.48
38	HPV51	E8^E2	KCFRYRFTKHKGLYK	109	123	HLA-DRB1*11:01	Consensus	0.48
39	HPV82	E8^E2	NTGGHLSATKTAFIV	86	100	HLA-DRB1*07:01	Consensus	0.48
40	HPV59	E8^E2	GLKCLRYRLRKVHWL	108	122	HLA-DRB1*11:01	Consensus	0.5
41	HPV26	E8^E2	LKCLRYRFKKHKGLY	121	135	HLA-DRB5*01:01	Consensus	0.54
42	HPV35	E8^E2	TLKCLRYRLGKYKAL	110	124	HLA-DRB5*01:01	Consensus	0.54
43	HPV35	E8^E2	KCLRYRLGKYKALYQ	112	126	HLA-DRB5*01:01	Consensus	0.54
44	HPV18	E8^E2	QRTKFLNTVAIPDSV	148	162	HLA-DRB1*04:05	Consensus	0.55
45	HPV18	E8^E2	RTKFLNTVAIPDSVQ	149	163	HLA-DRB1*04:05	Consensus	0.55
46	HPV51	E8^E2	TNCLKCFRYRFTKHK	105	119	HLA-DRB5*01:01	Consensus	0.55
47	HPV51	E8^E2	NCLKCFRYRFTKHKG	106	120	HLA-DRB5*01:01	Consensus	0.55
48	HPV53	E8^E2	YRFQKHKQLFVTVSS	131	145	HLA-DRB1*07:01	Consensus	0.56
49	HPV18	E8^E2	TQRTKFLNTVAIPDS	147	161	HLA-DRB1*04:05	Consensus	0.57
50	HPV18	E8^E2	TKFLNTVAIPDSVQI	150	164	HLA-DRB1*04:05	Consensus	0.57
51	HPV26	E8^E2	SLKCLRYRFKKHKGL	120	134	HLA-DRB5*01:01	Consensus	0.57
52	HPV33	E8^E2	KPYKELYSSMSSTWH	107	121	HLA-DRB1*04:05	Consensus	0.57
53	HPV52	E8^E2	RQQFLKTVKIPNTVQ	159	173	HLA-DRB1*11:01	Consensus	0.59
54	HPV59	E8^E2	NGLKCLRYRLRKVHW	107	121	HLA-DRB1*11:01	Consensus	0.59
55	HPV18	E8^E2	ETQRTKFLNTVAIPD	146	160	HLA-DRB1*04:05	Consensus	0.6
56	HPV33	E8^E2	KPYKELYSSMSSTWH	107	121	HLA-DRB1*04:01	Consensus	0.66
57	HPV56	E8^E2	RYRFQKYKTLFVDVT	120	134	HLA-DRB1*07:01	Consensus	0.68
58	HPV31	E8^E2	LRYRLSKYKQLYEQV	120	134	HLA-DRB5*01:01	Consensus	0.7
59	HPV53	E8^E2	QKHKQLFVTVSSTYH	134	148	HLA-DRB1*07:01	Consensus	0.7
60	HPV26	E8^E2	NSLKCLRYRFKKHKG	119	133	HLA-DRB5*01:01	Consensus	0.72
61	HPV31	E8^E2	GDANILKCLRYRLSK	112	126	HLA-DRB1*11:01	Consensus	0.72
62	HPV59	E8^E2	KNGLKCLRYRLRKVH	106	120	HLA-DRB1*11:01	Consensus	0.72
63	HPV53	E8^E2	KHKQLFVTVSSTYHW	135	149	HLA-DRB1*07:01	Consensus	0.73
64	HPV18	E8^E2	RNSLKCLRYRLRKHS	102	116	HLA-DRB1*11:01	Consensus	0.74
65	HPV31	E8^E2	LKCLRYRLSKYKQLY	117	131	HLA-DRB1*11:01	Consensus	0.74
66	HPV18	E8^E2	NSLKCLRYRLRKHSD	103	117	HLA-DRB1*11:01	Consensus	0.78
67	HPV18	E8^E2	SLKCLRYRLRKHSDH	104	118	HLA-DRB1*11:01	Consensus	0.78
68	HPV18	E8^E2	LKCLRYRLRKHSDHY	105	119	HLA-DRB1*11:01	Consensus	0.78
69	HPV18	E8^E2	KCLRYRLRKHSDHYR	106	120	HLA-DRB1*11:01	Consensus	0.78
70	HPV45	E8^E2	KNSLKCLRYRLRKYA	104	118	HLA-DRB1*11:01	Consensus	0.81
71	HPV82	E8^E2	CLRYRFAKHRNLFKE	111	125	HLA-DRB1*11:01	Consensus	0.81
72	HPV45	E8^E2	LKCLRYRLRKYADHY	107	121	HLA-DRB1*11:01	Consensus	0.83
73	HPV53	E8^E2	KCLRYRFQKHKQLFV	127	141	HLA-DRB5*01:01	Consensus	0.84
74	HPV45	E8^E2	NSLKCLRYRLRKYAD	105	119	HLA-DRB1*11:01	Consensus	0.85
75	HPV45	E8^E2	SLKCLRYRLRKYADH	106	120	HLA-DRB1*11:01	Consensus	0.85
76	HPV82	E8^E2	TGGHLSATKTAFIVH	87	101	HLA-DRB1*07:01	Consensus	0.85
77	HPV82	E8^E2	TNCLKCLRYRFAKHR	106	120	HLA-DRB5*01:01	Consensus	0.86
78	HPV82	E8^E2	NCLKCLRYRFAKHRN	107	121	HLA-DRB5*01:01	Consensus	0.86
79	HPV53	E8^E2	HKQLFVTVSSTYHWT	136	150	HLA-DRB1*07:01	Consensus	0.88
80	HPV35	E8^E2	ANTLKCLRYRLGKYK	108	122	HLA-DRB1*11:01	Consensus	0.9
81	HPV35	E8^E2	ANTLKCLRYRLGKYK	108	122	HLA-DRB5*01:01	Consensus	0.95
82	HPV35	E8^E2	NTLKCLRYRLGKYKA	109	123	HLA-DRB5*01:01	Consensus	0.95
83	HPV51	E8^E2	LKCFRYRFTKHKGLY	108	122	HLA-DRB1*11:01	Consensus	0.97
84	HPV82	E8^E2	LRYRFAKHRNLFKEV	112	126	HLA-DRB1*11:01	Consensus	0.97
85	HPV68	E8^E2	KNGLKCLRYRLQKHN	104	118	HLA-DRB1*11:01	Consensus	0.99
86	HPV73	E8^E2	ITLMFTTVLQQQHFL	128	142	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.65
87	HPV73	E8^E2	VITLMFTTVLQQQHF	127	141	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.68
88	HPV73	E8^E2	TLMFTTVLQQQHFLQ	129	143	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.78
89	HPV73	E8^E2	GVITLMFTTVLQQQH	126	140	HLA-DPA1*02:01/DPB1*14:01	NetMHCIIpan	0.95